Can I Butt In?

Bowel Research UK CEO Kathryn Pretzel-Shiels is joined by members of the AMELIE project team to discuss this groundbreaking research. AMELIE (Anchored Muscle cells for Incontinence) aims to help people with faecal incontinence due to anal sphincter injury, particularly women who have experienced this injury through childbirth. In this clinical trial, muscle cells are attached to microcarriers and implanted as part of regenerative cell therapy to restore muscle function. Professor Richard Day, Professor Charlie Knowles, and Dr Marina Yiasemidou discuss their roles, the progress and challenges of this research so far, and the potential benefits to patients in the future.
Read the transcript for this episode.
Find out more about the AMELIE project
Follow AMELIE on X: @amelieproject, and on Instagram and Threads: @amelie.project.eu
Find out more about Bowel Research UK
Music is “Summer Guitar” by Amaksi from Pixabay.

Sam rounds up the last 24 episodes of Can I Butt In? We take a look back at each episode, our guests, the topics, and insightful conversations with bowel cancer and bowel disease patients and researchers.
Can I Butt In? is taking a break! We’ll see you again later on with a new host and a range of new guests and themes to dig into.
Read the transcript for this episode.
Find out more about Bowel Research UK.
Music is “Summer Guitar” by Amaksi from Pixabay and Melancholic Guitar Sting Transitions by VoiceBosch.

Sam rewinds to last year’s Big Bowel Event, resharing a session called PaRT Life. In this session, three members of the PaRT network discussed their patient experiences and their experiences of getting involved in research. The members are Steve Clark, Alicia Cropley, and Nigel Horwood. Sam also provides details on the upcoming Big Bowel Event 2024, taking place online on 22nd August.
Register for the Big Bowel Event 2024.
Watch the Big Bowel Event 2023 on YouTube.
Read the transcript for this episode.
Find out more about Bowel Research UK.
Music is “Summer Guitar” by Amaksi from Pixabay.

In the second of this two-part series on the spread of bowel cancer to the peritoneum, Sam is joined by Becky Maskill and Rebecca (Bex) Halstead. Becky has experience of peritoneal metastases, and Bex is Lead Colorectal/Peritoneal Tumour Clinical Nurse Specialist at The Christie NHS Foundation Trust. Becky tells her patient story, Bex explains what her role involves, and the two discuss their long relationship since Becky’s diagnosis nearly ten years ago.
 
Find out more about the Colorectal and Peritoneal Oncology Centre (CPOC) at The Christie
Read the transcript for this episode
Find out more about Bowel Research UK
Music is “Summer Guitar” by Amaksi from Pixabay.

Sam is joined by Dr Meera Patel to talk about her research into the spread of bowel cancer to the peritoneum. Meera is an Academic Clinical Lecturer at The University of Manchester and a trainee bowel surgeon, splitting her time equally between her academic medical research work and her clinical practice treating patients in the Northwest of England. Sam and Meera discuss what the peritoneum is, how cancer can spread there and how it’s treated. Meera explains her research into the connection between this spread, bacteria, and the microbiome.
Peritoneal Metastases - Manchester Cancer Research Centre
Read the transcript for this episode
Find out more about Bowel Research UK
Music is “Summer Guitar” by Amaksi from Pixabay.

Sam presented at Oncology Professional Care conference on 22nd May 2024 and provides a rerun of those presentations in this episode. The first presentation is on patient and public involvement (PPI), including what it is, how it is done at Bowel Research UK, and debunking nine common PPI misconceptions. The second talk is based on Sam’s patient experiences of navigating the healthcare system with a genetic predisposition to cancer. Artist Francesco Tassi drew visual minutes for the talks from Sam, fellow patients and fellow presenter and Lynch syndrome National Lead Nurse, Laura Monje-Garcia.
View the visual minutes and read the transcript for this episode.
Find out more about Bowel Research UK.
Music is “Summer Guitar” by Amaksi from Pixabay and Melancholic Guitar Sting Transitions by VoiceBosch.